| Picture
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Name
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Role in Seinfeld
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Role on The Simpsons
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Jason Alexander
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Played George Costanza.
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Voiced Bourbon Verlander in the season 28 episode "The Caper Chase".
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Nick Bakay
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Played Carl in "The Smelly Car".
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Voiced Salem Saberhagen in the season 15 episode "Milhouse Doesn't Live Here Anymore".
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Bob Balaban
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Played Russell Dalrymple in "The Pitch", "The Ticket", "The Watch", "The Shoes" and "The Pilot",
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Voiced the narrator in the season 32 episode "The Dad-Feelings Limited".
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Wren T. Brown
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Played an AIDS Walk participant in "The Sponge".
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Voiced Virgil in the season 21 episode "The Color Yellow".
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Michael Chiklis
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Played Steve in "The Stranded".
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Voiced the handsome quarterback in the season 28 episode "The Town".
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Christopher Collins
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Played a thug in "The Subway".
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Original voice of Mr. Burns and Moe.
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Bryan Cranston
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Played Tim Whatley in "The Mom and Pop Store", "The Label Maker", "The Jimmy", "The Yada Yada", and "The Strike".
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Voiced Stradivarius Cain in the season 23 episode "The Spy Who Learned Me".
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Illeana Douglas
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Played Loretta in "The Strongbox".
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Voiced a new age clerk in the season 30 episode "Crystal Blue-Haired Persuasion".
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Janeane Garofalo
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Played Jeannie Steinman in "The Invitations" and "The Foundation".
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Voiced herself in the season 9 episode "The Last Temptation of Krust" and the season 23 episode "The Ten-Per-Cent Solution".
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Brian George
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Played Baby Bhatt in "The Cafe", "The Visa" and "The Finale".
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Voiced several British men in the season 32 episode "The 7 Beer Itch" and MI5 agents in the season 32 episode "The Man from G.R.A.M.P.A.".
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Kathie Lee Gifford
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Played herself in "The Opposite".
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Played herself in the season 10 episode "Treehouse of Horror IX", via live-action recording.
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Dana Gould
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Played Frankie Merman in "The Junk Mail".
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Worked as a co-executive producer and writer from season 12 to season 19, and had also served as a guest star for the show.
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Kathy Griffin
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Played Sally Weaver in "The Doll" and "The Cartoon".
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Voiced Francine Rhenquist in the season 12 episode "Bye, Bye, Nerdie".
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Carol Kane
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Played Corinne in the The Marine Biologist".
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Voiced Maggie Simpson and Springfield Plasma Center nurse in the season 2 episode "Bart vs. Thanksgiving" and Blythe in season 34 episode Step Brother from the Same Planet.
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Katherine LaNasa
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Played Sgt. Cathy Tierny in "The Beard".
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Voiced an unknown character in the season 37 episode "Irrational Treasure".
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Jane Leeves
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Played Marla Penny in "The Virgin", "The Contest", "The Pilot, Part 2" and "The Finale, Part 2.".
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Voiced Edwina in the season 15 episode "The Regina Monologues".
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Jay Leno
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Played himself in "The Shower Head".
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Voiced himself in the season 9 episode "The Last Temptation of Krust" and the season 27 episode "To Courier with Love".
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David Letterman
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Played himself during the closing credits of "The Abstinence".
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Voiced himself in the Season 23 episode "The D'oh-cial Network".
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Tracy Letts
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Played a counterguy in "The Strike".
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Voiced himself in the season 36 episode "Desperately Seeking Lisa".
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Julia Louis-Dreyfus
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Played Elaine Benes.
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Voiced Gloria in the season 13 episode "A Hunka Hunka Burns in Love", the season 19 episode "I Don't Wanna Know Why the Caged Bird Sings", and the season 20 episode "Sex, Pies and Idiot Scrapes".
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Jon Lovitz
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Played Gary Fogel in "The Scofflaw".
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Voiced Professor Lombardo, Aristotle Amadopolis, Artie Ziff, Llewellyn Sinclair and Jay Sherman.
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Bette Midler
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Played herself in "The Understudy".
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Voiced herself in the season 4 episode "Krusty Gets Kancelled".
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Megan Mullally
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Played Betsy in "The Implant".
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Voices Sarah Wiggum from the season 32 episode "Uncut Femmes" onward.
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Bob Odenkirk
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Played Ben in "The Abstinence".
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Voiced the mob lawyer in the season 31 episode "The Fat Blue Line".
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Patton Oswalt
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Played video store clerk in "The Couch".
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Voiced T-Rex in the season 24 episode "The Day the Earth Stood Cool" and Bart's guilt in the season 28 episode "The Cad and the Hat" and wrote the Bart Simpson's Treehouse of Horror comic story They Draw.
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Chris Parnell
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Plyaed Stu Crespi in "The Butter Shave".
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Voiced the surgeon fiancé in the season 32 episode "A Springfield Summer Christmas for Christmas".
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Regis Philbin
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Played himself in "The Opposite".
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Played himself in the season 10 episode "Treehouse of Horror IX", via live-action recording.
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Brian Posehn
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Played Artie in "The Burning".
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Voiced Dumlee in the season 28 episode "A Father's Watch".
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Stephen Root
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Played Mr. Lager in "The Invitations".
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Voiced Bildorf in the season 32 episode "Wad Goals".
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Bill Saluga
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Played an usher in "The Opera".
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Voiced Ray J. Johnson in the season 13 episode "The Old Man and the Key".
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Molly Shannon
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Played Sam in "The Summer of George".
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Voiced Katya in the season 36 episode "Desperately Seeking Lisa".
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Sab Shimono
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Played Executive #1 in "The Checks".
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Voiced the master sushi chef in the Season 2 episode "One Fish, Two Fish, Blowfish, Blue Fish", Mr. Sparkle in the Season 8 episode "In Marge We Trust", and a Gruff Japanese sailor in the season 18 episode "The Wife Aquatic".
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Sarah Silverman
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Played Emily in "The Money".
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Voiced Nikki McKenna in the season 21 episode "Stealing First Base" and the season 24 episode "Moonshine River", herself in the season 26 episode "Clown in the Dumps", and Rachel Cohen in the season 28 episode "Treehouse of Horror XXVII".
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Lawrence Tierney
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Played Alton Benes in "The Jacket".
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Voiced Don Brodka in the season 7 episode "Marge Be Not Proud".
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Stephen Tobolowsky
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Played Tor in "The Heart Attack".
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Voiced Merle in the season 37 episode "Aunt Misbehavin'".
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Marisa Tomei
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Played herself in "The Cadillac, Part 2".
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Voiced Sara Sloane in the season 14 episode "A Star Is Born Again".
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Robert Wagner
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Played Dr. Abbott in "The Yada Yada".
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Voiced himself in the season 16 episode "Goo Goo Gai Pan".
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Patrick Warburton
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Played David Puddy in several episodes over the course of several seasons.
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Voiced Joe Swanson in Family Guy" crossover episode The Simpsons Guy".
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George Wendt
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Cameoed as himself in "The Trip, Part 1".
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Voiced Norm Peterson in the season 6 episode "Fear of Flying".
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